Flexible Dosing

With the freedom and flexibility of Hizentra, patients can work with their prescriber to create an individualized treatment plan that best fits their lifestyle.

Based on certain criteria, such as body type, dose, and lifestyle, you and your doctor can design a highly individualized treatment plan that fits your needs.

Below are four sample patients with four different treatment plans. Each is able to infuse on a regular schedule and maintain steady state Ig levels, despite their different lifestyles.

Treatment Plan >

Meet Kevin

Second grader who infuses 2x/week

Kevin is a second-grader who enjoys sports and video games. Because of his activity level and low body fat, his parents and prescriber decided on a frequent infusion schedule, resulting in less volume and shorter infusions.

Meet Kevin >

Treatment Plan

May be best for: Steady-state IgG levels, low body fat, and shorter infusion times

Treatment Plan >

Meet Sarah

Busy mother who infuses weekly

Sarah is a busy mom with 2 kids who doesn't have much spare time. Because of her schedule, she likes to keep a weekly routine, infusing Hizentra on her Sunday morning walk.

Meet Sarah >

Treatment Plan

May be best for: Steady-state IgG levels, infusing weekly, and routine schedules

Treatment Plan >

Meet Rose

Grandmother who infuses every 10 days

Rose is a grandmother of six who enjoys baking, knitting and playing cards. Rose prefers to infuse less frequently and finds it easy to remember to infuse on the 5th, 15th and 25th of every month.

Meet Rose >

Treatment Plan

May be best for: Steady-state IgG levels, less frequent infusions, and switching from 10% to 20%

Treatment Plan >

Meet Will

Athletic student who infuses biweekly (every two weeks)

Will is an athletic college student who lives on campus. Because of his privacy concerns with living in the dorm, he prefers to infuse less frequently.

Meet Will >

Treatment Plan

May be best for: Steady-state IgG levels, less frequent infusions, and switching from 10% to 20%

Adapts to Fit Your Changing Lifestyle

As your lifestyle changes over time, the flexibility of Hizentra lets you adapt your dosing schedule to maintain steady Ig levels while meeting your changing needs.

Your Tools for Administering Hizentra

At CSL Behring, we recognize that self-infusion of Ig therapy may be a new experience for healthcare professionals as well as their patients. Next find helpful information and tools on the dosing and administration of Hizentra.

Important Safety Information

Important Safety Information

WARNING: Thrombosis (blood clots) can occur with immune globulin products, including Hizentra. Risk factors can include: advanced age, prolonged immobilization, a history of blood clotting or hyperviscosity (blood thickness), use of estrogens, installed vascular catheters, and cardiovascular risk factors.

If you are at high risk of blood clots, your doctor will prescribe Hizentra at the minimum dose and infusion rate practicable and will monitor for signs of clotting events and hyperviscosity. Always drink sufficient fluids before infusing Hizentra.

See your doctor for a full explanation, and the full prescribing information for complete boxed warning.

Hizentra®, Immune Globulin Subcutaneous (Human), 20% Liquid, is a prescription medicine used to treat:

  • Primary immune deficiency (PI) in patients 2 years and older
  • Chronic inflammatory demyelinating polyneuropathy (CIDP) in adults

Treatment with Hizentra might not be possible if your doctor determines you have hyperprolinemia (too much proline in the blood), or are IgA-deficient with antibodies to IgA and a history of hypersensitivity. Tell your doctor if you have previously had a severe allergic reaction (including anaphylaxis) to the administration of human immune globulin. Tell your doctor right away or go to the emergency room if you have hives, trouble breathing, wheezing, dizziness, or fainting. These could be signs of a bad allergic reaction.

Inform your doctor of any medications you are taking, as well as any medical conditions you may have had, especially if you have a history of diseases related to the heart or blood vessels, or have been immobile for some time. Inform your physician if you are pregnant or nursing, or plan to become pregnant.

Infuse Hizentra under your skin only; do not inject into a blood vessel. Self-administer Hizentra only after having been taught to do so by your doctor or other healthcare professional, and having received dosing instructions for treating your condition.

Immediately report to your physician any of the following symptoms, which could be signs of serious adverse reactions to Hizentra:

  • Reduced urination, sudden weight gain, or swelling in your legs (possible signs of a kidney problem).
  • Pain and/or swelling or discoloration of an arm or leg, unexplained shortness of breath, chest pain or discomfort that worsens on deep breathing, unexplained rapid pulse, or numbness/weakness on one side of the body (possible signs of a blood clot).
  • Bad headache with nausea; vomiting; stiff neck; fever; and sensitivity to light (possible signs of meningitis).
  • Brown or red urine; rapid heart rate; yellowing of the skin or eyes; chest pains or breathing trouble; fever over 100°F (possible symptoms of other conditions that require prompt treatment).

Hizentra is made from human blood. The risk of transmission of infectious agents, including viruses and, theoretically, the Creutzfeldt-Jakob disease (CJD) agent and its variant (vCJD), cannot be completely eliminated.

The most common side effects in the clinical trials for Hizentra include redness, swelling, itching, and/or bruising at the infusion site; headache; chest, joint or back pain; diarrhea; tiredness; cough; rash; itching; fever, nausea, and vomiting. These are not the only side effects possible. Tell your doctor about any side effect that bothers you or does not go away.

Before receiving any vaccine, tell immunizing physician if you have had recent therapy with Hizentra, as effectiveness of the vaccine could be compromised.

Please see full prescribing information for Hizentra, including boxed warning and the patient product information.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

CSL Behring
Hizentra is manufactured by CSL Behring AG and distributed by CSL Behring LLC.
Hizentra® and MyHizentra® are registered trademarks of CSL Behring AG.
Biotherapies for Life® is a registered trademark of CSL Behring LLC.
CSL Behring AssuranceSM, IgIQSM, and Premier StartSM are service marks of CSL Behring LLC.
Voice2Voice® is a registered trademark of CSL Behring GmbH.
© 2018 CSL Behring LLC. The product information presented on this site is intended for US residents only. HIZ-0316-MAR18